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KMID : 0921620150450010051
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Journal of Bacteriology and Virology
2015 Volume.45 No. 1 p.51 ~ p.53
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ISAba15 Inserted into Outer Membrane Protein Gene carO in Acinetobacter baumannii
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Kim Dae-Hun
Ko Kwan-Soo
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Abstract
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We identified ISAba15 inserted into the carO gene in an Acinetobacter baumannii isolate. The insert disrupted the lpxD gene, resulting in colistin resistance in A. baumannii. Persistence in carbapenem resistance in A. baumannii isolates with an intact carO gene indicates that loss of the encoded CarO may play a minor role in carbapenem resistance.
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KEYWORD
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Carbapenem, Insertion sequence (IS), Antimicrobial resistance
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